Scientist II

The Scientist II helps advance LGC CDx’s purpose of understanding disease by supporting the research and development of new precision diagnostic products. Support includes independently performing routine and non-routine applications of cellular/molecular biology technology to quantify and manipulate genetic material.

Assist in leading the R&D Teams to promote a high performance, innovative culture.

Mentor junior scientists within R&D and other departments to promote their independence, problem solving skills and technical expertise.

Develop reference materials for clinical diagnostics. Understanding how our customers’ assays work is a critical part of this process. This requires reading and assessing product literature and scientific research articles.

Manage and mentor research technicians within the R&D team and mentor others outside of the department.

Perform general molecular techniques such as nucleic acid purification, gel-electrophoresis, RNA transcription, cell culture, and bacterial culture.

Perform nucleic acid analysis (RNA/DNA integrity analysis, real time qPCR, digital PCR) and analyze results.

Design new biosynthetic constructs or primers/probes for use in new products.

Develop processes for manufacture and testing of new products. Draft SOPs for new processes and perform method validations as appropriate.

Plan and execute experiments and tasks as assigned according to the timelines and ensure documentation meets GLP/GMP requirements.

Culture cells using aseptic techniques. Introduce nucleic acids into cultured cells.

Organize projects and data using Excel, Word, PowerPoint and a document control system (EtQ).

Record test results and data records, seek appropriate approval and file according to established procedures.

Maintain, calibrate, and operate equipment according to established protocols. Monitor equipment for appropriate operation within set parameters and investigate abnormal results.

Plan for raw material requirements by maintaining appropriate inventory of reagents and ordering reagents as needed through an ERP system (SAP).

Maintain a clean and safe lab environment.

Maintain accurate records in laboratory notebooks.

Transfer designs to other individuals and groups in R&D and manufacturing, including training and writing standard operating procedures (SOPs) and design history records (DHRs).

As necessary, validate new equipment, and ensuring that equipment is operating properly.

Initiate and perform process improvement studies and update SOPs as required.

Work in collaboration with the Quality Assurance group to fulfil Quality Management Goals and proactively address problems under an ISO quality system.

Evaluate alternative reagents, develop purchasing specifications and plan for project raw material requirements by maintaining appropriate inventory of reagents.