Simran Gupta

Entry-Level Bioinformatician · NGS & Genomics

Agra, Uttar Pradesh, India

@simran_gupta1

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About

B.Tech Biotechnology graduate pursuing an Advanced Diploma in Bioinformatics, with practical training in NGS, genomic data analysis, sequence analysis, and variant analysis. Experienced with R, Python/Biopython, Linux/Bash, and bioinformatics databases and workflows, and seeking an entry-level role in bioinformatics and computational genomics.

Experience

Research Intern

Helix Biogenesis Pvt. Ltd. · Noida, Uttar Pradesh

Jul 2025 – Sep 2025

Performed core laboratory procedures including DNA isolation, PCR amplification and microbial culture workflows. Applied aseptic technique and laboratory safety protocols while maintaining accurate experimental documentation and records.
Internship Trainee

Rapture Biotech International Pvt. Ltd. · Noida, Uttar Pradesh

Jul 2025 – Aug 2025

Trained across biochemistry, immunology and cell biology laboratory techniques, gaining hands-on exposure to core wet-lab methods. Performed enzyme assays and protein analysis while maintaining accurate experiment records and documentation.

Education

2026

B.Tech

Anand Engineering College

Awarded by AKTU

Biotechnology · 2022 – May 2026

Biotechnology · 2022 – May 2026
2026

Advanced Diploma in Bioinformatics

Win In Life Academy

Awarded by CliniLaunch Research Institute / Win In Life Academy

Bioinformatics · Jun 2026

Bioinformatics · Jun 2026

Skills

3 to 6 months

PCR Cell Culture DNA Extraction Aseptic techniques

<3 months

R Pdb AWK Bash Python Nextflow Enzyme Assays Variant Calling Protein Analysis Sequence analysis Data Visualization Gel electrophoresis Statistical Analysis Technical Documentation Biological data interpretation

Tools / apps / platforms

<3 months

Git NCBI dbSNP Linux PyMOL GROMACS UniProt Basic Local Alignment Search Tool BLAST

Projects

Protein–Ligand Molecular Docking of PQQ with Quinoprotein Glucose Dehydrogenase

AutoDock Vina, SwissDock, PDB, PyMOL, UCSF Chimera

Docked PQQ against quinoprotein glucose dehydrogenase and analyzed binding poses and protein–ligand interactions to assess docking outcomes.
Global Sequence Alignment — Needleman–Wunsch Algorithm

Python

Implemented the Needleman–Wunsch dynamic programming algorithm to align nucleotide sequences and verify alignment scores and sequence identity.
Linux-Based FASTA Sequence Processing

Linux, awk, Bash

Merged multiple FASTA files using Linux command-line utilities, counted and cross-verified sequence records with awk, and automated repetitive sequence-handling tasks using Bash scripting.
NGS & Genomic Data Analysis

NCBI, SRA, GEO, RefSeq

Processed NGS datasets and genomic data formats to practice sequence analysis, variant calling, and genome annotation workflows. Queried dbSNP and explored population genomics datasets to interpret variant frequency data.

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