Simran Gupta

About

B.Tech Biotechnology graduate pursuing an Advanced Diploma in Bioinformatics, with practical training in NGS, genomic data analysis, sequence analysis, and variant analysis. Experienced with R, Python/Biopython, Linux/Bash, and bioinformatics databases and workflows, and seeking an entry-level role in bioinformatics and computational genomics.

Experience

• Research Intern
  Helix Biogenesis Pvt. Ltd. · Noida, Uttar Pradesh
  Jul 2025 – Sep 2025

  Performed core laboratory procedures including DNA isolation, PCR amplification and microbial culture workflows. Applied aseptic technique and laboratory safety protocols while maintaining accurate experimental documentation and records.

• Internship Trainee
  Rapture Biotech International Pvt. Ltd. · Noida, Uttar Pradesh
  Jul 2025 – Aug 2025

  Trained across biochemistry, immunology and cell biology laboratory techniques, gaining hands-on exposure to core wet-lab methods. Performed enzyme assays and protein analysis while maintaining accurate experiment records and documentation.

Education

• B.Tech
  Anand Engineering College · AKTU
  Biotechnology · 2022 – May 2026
• Advanced Diploma in Bioinformatics
  Win In Life Academy · CliniLaunch Research Institute / Win In Life Academy
  Bioinformatics · Jun 2026

Skills

• Data Visualization <3 months
• Python <3 months
• Cell Culture 3 to 6 months
• DNA Extraction 3 to 6 months
• Bash <3 months
• Technical Documentation <3 months
• Statistical Analysis <3 months
• PCR 3 to 6 months
• R <3 months
• Protein Analysis <3 months
• Aseptic techniques 3 to 6 months
• Sequence analysis <3 months
• Gel electrophoresis <3 months
• Biological data interpretation <3 months
• Enzyme Assays <3 months
• Variant Calling <3 months
• Nextflow <3 months
• Pdb <3 months
• AWK <3 months

Tools / apps / platforms

• Basic Local Alignment Search Tool BLAST <3 months
• dbSNP <3 months
• Git <3 months
• GROMACS <3 months
• Linux <3 months
• NCBI <3 months
• PyMOL <3 months
• UniProt <3 months

Projects

• Protein–Ligand Molecular Docking of PQQ with Quinoprotein Glucose Dehydrogenase
  AutoDock Vina, SwissDock, PDB, PyMOL, UCSF Chimera

  Docked PQQ against quinoprotein glucose dehydrogenase and analyzed binding poses and protein–ligand interactions to assess docking outcomes.

• Global Sequence Alignment — Needleman–Wunsch Algorithm
  Python

  Implemented the Needleman–Wunsch dynamic programming algorithm to align nucleotide sequences and verify alignment scores and sequence identity.

• Linux-Based FASTA Sequence Processing
  Linux, awk, Bash

  Merged multiple FASTA files using Linux command-line utilities, counted and cross-verified sequence records with awk, and automated repetitive sequence-handling tasks using Bash scripting.

• NGS & Genomic Data Analysis
  NCBI, SRA, GEO, RefSeq

  Processed NGS datasets and genomic data formats to practice sequence analysis, variant calling, and genome annotation workflows. Queried dbSNP and explored population genomics datasets to interpret variant frequency data.