RESEARCH FELLOW

IRCCS San Raffaele Scientific Institute in Milan, Italy, is seeking a Research Fellow to join the Tumor Biology and Vascular Targeting Unit of the Division of Experimental Oncology. Long-term commitment of Tumor biology and vascular targeting Unit is to understand the role of inflammatory cytokines and chromogranin A in cancer biology, and to develop new strategies for cancer therapy based on the manipulation of the tumor vasculature with targeted cytokines and anti-angiogenic agents, in order to improve the penetration of chemotherapeutic drugs and the infiltration of cells of the immune system in tumor tissues.

The candidate will work on a project supported by the EU (TRANSCAN-3 JTC 2022) focused on glioblastoma, a type of brain tumor. Specifically, the project regards the development of novel translational approaches to tackle glioblastoma using peptide-cytokine fusion products in combination with new tumor targeted-nanomedicine, and the evaluation of their anti-tumor properties and mechanisms of action in in vitro and in vivo murine models.

Main responsibilities:

• maintenance of cell cultures
• flow cytometry and immunohistochemistry analysis
• biochemical analyses (such as ELISA, SDS-PAGE, and WB)
• in vivo drug efficacy studies in tumor-bearing mice
• quantitative-RT PCR

The candidate we are looking for has the following skills:

• highly motivated and interested in tumor biology and translational research
• Master’s degree in biological sciences, biotechnology, or related disciplines. Doctoral degree is optional
• skills in protein biochemistry, cell biology, flow cytometry, immunohistochemistry
• experience in, or willingness to learn, how to perform experiments in mice
• research planning and organization skills

What we offer:

• type of contract: collaboration (Co.Co.Co), salary will be commensurate with the research experience and CV of the applicant
• duration: one year, renewable up to two years
• place of work: IRCCS San Raffaele Hospital, Via Olgettina, number 60 – Milan (Italy)

At San Raffaele Scientific Institute, a world-renowned center of excellence for clinical and scientific activities, we believe that considering diversity and promoting an open and inclusive environment is crucial to our success. We are committed to ensure that equal employment opportunities are provided and based on merit without regard to age, religion, sex, disability, medical condition, sexual orientation, cultural and social backgrounds, gender identity or expression, national or ethnic origin, or any other legally recognized status entitled to protection under applicable laws. We offer attractive conditions and rewards appropriate to an internationally competitive research organization.